Childhood Acute Lymphoblastic Leukemia and Indicators of Early Immune Stimulation: A Childhood Leukemia International Consortium Study
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چکیده
منابع مشابه
Childhood acute lymphoblastic leukemia and indicators of early immune stimulation: a Childhood Leukemia International Consortium study.
The associations between childhood acute lymphoblastic leukemia (ALL) and several proxies of early stimulation of the immune system, that is, day-care center attendance, birth order, maternally reported common infections in infancy, and breastfeeding, were investigated by using data from 11 case-control studies participating in the Childhood Leukemia International Consortium (enrollment period:...
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Abstract Background Leukemia is the most prevalent childhood cancer and Acute Lymphoblastic Leukemia (ALL) constitutes 75% of all cases. The most frequent presenting symptoms are fever, weight loss and pallor. Early detection of clinical symptoms positively affects timely diagnosis. The objectives of the present study were to assess frequency of presenting symptoms, laboratory data, immune ph...
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Background: Acute Lymphoblastic Leukemia (ALL) is the most prevalent cancer in childhood. ALL is a heterogeneous type of malignancy and treatment protocols vary based on the immunological classification of ALL. The critical step for treating ALL is immunological subgroup identification by flow cytometry findings. In this study, for the first time, immunophenotypic information was evaluated in c...
متن کاملChildhood Acute Lymphoblastic Leukemia.
The cure rate for childhood acute lymphoblastic leukemia (ALL) now exceeds 70%. This success has been achieved in part by improvements in the biologic characterization of newly diagnosed patients. Modern treatment protocols rely on this information to tailor therapy to a patient's risk of relapse. Patients with favorable genetic features, such as hyperdiploidy or the TEL-AML1 fusion, can be tre...
متن کاملChildhood Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia (ALL) is recognized as a fast-developing cancer originated from blood-progenitor cells. Blasts cells are immature cells which generate white blood cells (leukocytes), and it is the malignancy of the blast cells which lead to leukemias. The bone marrow is gradually filled up with these blasts and as a result, the production of healthy blood cells will be damaged. Mal...
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ژورنال
عنوان ژورنال: American Journal of Epidemiology
سال: 2015
ISSN: 0002-9262,1476-6256
DOI: 10.1093/aje/kwu298